Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 3/20 | 0.46 |
| ▸ | HNF4A | P41235 | 2/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712544 | 0.90 | NR4A1 (0.50) | ATMCDC25BMEN1RAB9AKMT2A | |
| SCHEMBL11322771 | 0.87 | SRD5A2 (0.49) | ATMCDC25BMCL1MAPTTDP1 | |
| SCHEMBL10640903 | 0.81 | MEN1 (0.59) | ATMMEN1LMNAMAPTRAB9A | |
| SCHEMBL27281349 | 0.80 | CDC25B (0.63) | ATMCDC25BGSTA1ACMSDHNF4A | |
| SCHEMBL4376001 | 0.80 | POLB (0.49) | LMNAMAPTAKR1C3 | |
| SCHEMBL3154810 | 0.80 | ALDH1A1 (0.52) | ATMMEN1LMNAMAPTRAB9A | |
| SCHEMBL1331831 | 0.78 | AKR1C3 (0.57) | ATMCDC25BMEN1LMNAMAPT | |
| SCHEMBL64069 | 0.78 | AKR1C3 (0.57) | ATMCDC25BMEN1LMNAMAPT | |
| SCHEMBL8708830 | 0.77 | CDC25B (0.70) | ATMCDC25BGSTA1ACMSDHNF4A | |
| SCHEMBL5959807 | 0.77 | CYP2C9 (0.58) | ATMCDC25BGSTA1ACMSDHNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450585-A2 | Process for the manufacture of 2-deoxy-D-threo-pentofuranosides, intermediates for their manufacture and their use | CHEMPROSA, CHEMISCHE PRODUKTE SAISCHEK GmbH (AT) | 1991-10-09 | — | — | EP | disclosed |