Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844033 | 0.91 | AGTR1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9844151 | 0.89 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9843791 | 0.89 | AGTR1 (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL9843777 | 0.88 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9843949 | 0.84 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL13474406 | 0.84 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9402081 | 0.84 | AGTR1 (0.48) | AGTR1AGTR2 | |
| SCHEMBL9401976 | 0.83 | AGTR1 (0.52) | AGTR1AGTR2PPARG | |
| SCHEMBL9845667 | 0.83 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9402040 | 0.82 | AGTR1 (0.47) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407342-A2 | Pyrimidine derivatives | CIBA-GEIGY AG (CH) | 1991-01-09 | — | — | EP | disclosed |