Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.57 |
| ▸ | CYP11B1 | P15538 | 12/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 12/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 9/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9843743 | 0.85 | CYP19A1 (0.56) | CYP19A1CYP11B1CYP11B2CYP17A1TBXAS1 | |
| SCHEMBL2352944 | 0.84 | CYP19A1 (0.62) | CYP19A1CYP11B1CYP11B2CYP17A1TBXAS1 | |
| Hydrochloric Acid SCHEMBL9844004 | 0.83 | CYP19A1 (0.61) | CYP19A1CYP11B1CYP11B2CYP17A1TBXAS1 | |
| SCHEMBL2352579 | 0.83 | CYP19A1 (0.52) | CYP19A1CYP11B1CYP11B2CYP17A1TBXAS1 | |
| SCHEMBL8869750 | 0.76 | CYP19A1 (0.69) | CYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL2355216 | 0.73 | CYP19A1 (1.00) | CYP19A1CYP11B1CYP11B2CYP17A1 | |
| Hydrochloric Acid SCHEMBL9844041 | 0.72 | CYP19A1 (0.98) | CYP19A1CYP11B1CYP11B2CYP17A1 | |
| Hydrochloric Acid SCHEMBL9843801 | 0.71 | CYP19A1 (0.59) | CYP19A1CYP11B1CYP11B2CYP17A1TBXAS1 | |
| SCHEMBL7573772 | 0.68 | TBXAS1 (0.46) | CYP19A1CYP11B1CYP11B2TBXAS1 | |
| SCHEMBL27347321 | 0.62 | TBXAS1 (0.58) | CYP19A1CYP11B1CYP11B2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445073-A1 | Benzofurans | CIBA-GEIGY AG (CH) | 1991-09-04 | — | — | EP | disclosed |