Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861221 | 0.98 | ALDH1A1 (0.38) | ALDH1A1BACE1MEN1NPC1POLB | |
| SCHEMBL9843903 | 0.96 | ALDH1A1 (0.37) | ALDH1A1BACE1MEN1NPC1POLB | |
| SCHEMBL28393151 | 0.87 | — | — | |
| SCHEMBL11410392 | 0.80 | CYP1A2 (0.30) | DPP4 | |
| SCHEMBL11779659 | 0.79 | ALDH1A1 (0.34) | ALDH1A1BACE1 | |
| SCHEMBL10929994 | 0.78 | ALDH1A1 (0.38) | ALDH1A1BACE1 | |
| SCHEMBL10927098 | 0.78 | ALDH1A1 (0.38) | ALDH1A1BACE1 | |
| SCHEMBL873082 | 0.78 | MEN1 (0.38) | MEN1POLBKMT2A | |
| SCHEMBL11617059 | 0.78 | MEN1 (0.38) | MEN1POLBKMT2A | |
| SCHEMBL3817812 | 0.76 | ALDH1A1 (0.37) | ALDH1A1BACE1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414262-A2 | Process for the preparation of cyclic amino anticonvulsant compounds | WARNER-LAMBERT COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |