SCHEMBL9844108

SCHEMBL9844108

NC(=O)C(Cl)(CF)Oc1csnn1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11173188 0.67
SCHEMBL8110384 0.64 ALDH1A1 (0.34) NPC1RAB9AKMT2AALDH1A1ATM
SCHEMBL3242462 0.64 ALDH1A1 (0.38) NPC1RAB9AKMT2AALDH1A1ATM
SCHEMBL8132370 0.60 NPC1 (0.38) NPC1RAB9AKMT2AALDH1A1ATM
SCHEMBL9231936 0.60 KDM4E (0.38) NPC1RAB9AKMT2AALDH1A1ATM
SCHEMBL10772449 0.59
SCHEMBL3171518 0.59
SCHEMBL9671203 0.57 KMT2A (0.34) KMT2AALDH1A1ATML3MBTL1
SCHEMBL9671206 0.56 NPC1 (0.32) NPC1RAB9AALDH1A1ATML3MBTL1
SCHEMBL16034397 0.56 INPPL1 (0.39) KMT2AALDH1A1ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0443164-A1 Chlorofluoromethyl-thiadiazolyloxyacetic acidamide BAYER AG (DE) 1991-08-28 EP disclosed