Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 8/20 | 0.57 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9844056 | 0.99 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1ADRA2CTBXAS1 | |
| Hydrochloric Acid SCHEMBL9843934 | 0.80 | CYP11B1 (0.53) | CYP11B1CYP11B2CYP19A1TBXAS1CYP17A1 | |
| SCHEMBL9843977 | 0.76 | CYP11B1 (0.57) | CYP11B1CYP11B2CYP19A1ADRA2CTBXAS1 | |
| Hydrochloric Acid SCHEMBL9688409 | 0.75 | CYP19A1 (0.54) | CYP11B1CYP11B2CYP19A1ADRA2CTBXAS1 | |
| Hydrochloric Acid SCHEMBL9844241 | 0.75 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1ADRA2CTBXAS1 | |
| SCHEMBL11493719 | 0.73 | TBXAS1 (0.72) | CYP11B1CYP11B2CYP19A1ADRA2CTBXAS1 | |
| SCHEMBL10853070 | 0.73 | CYP19A1 (0.72) | CYP11B1CYP11B2CYP19A1ADRA2CTBXAS1 | |
| SCHEMBL23218591 | 0.73 | CYP11B1 (0.45) | CYP11B1CYP11B2CYP19A1ADRA2CTBXAS1 | |
| SCHEMBL2798439 | 0.73 | CYP11B1 (0.62) | CYP11B1CYP11B2CYP19A1ADRA2CTBXAS1 | |
| SCHEMBL10860244 | 0.72 | CYP19A1 (0.54) | CYP11B1CYP11B2CYP19A1ADRA2CTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445073-A1 | Benzofurans | CIBA-GEIGY AG (CH) | 1991-09-04 | — | — | EP | disclosed |