Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29872151 | 0.81 | L3MBTL1 (0.49) | CYP2C19HIF1AL3MBTL1CYP1A2MAPT | |
| SCHEMBL7872409 | 0.80 | CYP2C19 (0.42) | CYP2C19HIF1AL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL10635095 | 0.80 | HIF1A (0.44) | CYP2C19HIF1ACYP1A2CYP3A4RECQL | |
| SCHEMBL28905042 | 0.77 | HDAC3 (0.50) | CYP2C19HIF1ACYP1A2CYP3A4RECQL | |
| SCHEMBL3982825 | 0.73 | CYP2C19 (0.53) | CYP2C19HIF1ACYP1A2CYP3A4RECQL | |
| SCHEMBL5213853 | 0.73 | HDAC3 (0.47) | CYP2C19HIF1ACYP1A2CYP3A4RECQL | |
| SCHEMBL28376940 | 0.73 | MAPT (0.55) | CYP2C19HIF1ACYP1A2CYP3A4RECQL | |
| SCHEMBL12386591 | 0.72 | PHF8 (0.50) | L3MBTL1MAPK1HDAC3HDAC1HDAC2 | |
| SCHEMBL2859890 | 0.72 | PHF8 (0.50) | HDAC3HDAC1HDAC2HDAC8MAPT | |
| SCHEMBL4441293 | 0.72 | MAPT (0.53) | CYP2C19HIF1ACYP1A2CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682964-B2 | Amide compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-06-20 | — | — | US | disclosed |
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | disclosed |