Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 5/20 | 0.63 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.63 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NMBR | P28336 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9200734 | 0.89 | SOAT1 (0.77) | SOAT1SOAT2ACAT1SMN1; SMN2TP53 | |
| SCHEMBL9641246 | 0.88 | SOAT1 (0.76) | SOAT1SOAT2ACAT1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL20591099 | 0.88 | SOAT1 (0.76) | SOAT1SOAT2ACAT1SMN1; SMN2TP53 | |
| SCHEMBL9818653 | 0.87 | SOAT1 (0.73) | SOAT1SOAT2ACAT1SMN1; SMN2TP53 | |
| SCHEMBL9678897 | 0.86 | SOAT1 (0.57) | SOAT1SOAT2ACAT1SMN1; SMN2TP53 | |
| SCHEMBL9818696 | 0.84 | SOAT1 (0.69) | SOAT1SOAT2ACAT1NMBR | |
| SCHEMBL9640319 | 0.83 | SOAT1 (0.68) | SOAT1SOAT2ACAT1SMN1; SMN2TP53 | |
| SCHEMBL9640371 | 0.82 | SOAT1 (0.67) | SOAT1SOAT2ACAT1SMN1; SMN2TP53 | |
| SCHEMBL9641191 | 0.82 | SOAT1 (0.67) | SOAT1SOAT2ACAT1SMN1; SMN2TP53 | |
| SCHEMBL9681083 | 0.81 | SOAT1 (0.57) | SOAT1SOAT2ACAT1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | claimed |
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | disclosed |