Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 18/20 | 0.79 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844208 | 0.95 | SIGMAR1 (0.78) | SIGMAR1GRM2 | |
| SCHEMBL9502924 | 0.94 | SIGMAR1 (0.82) | SIGMAR1GRM2 | |
| SCHEMBL9844444 | 0.91 | SIGMAR1 (0.80) | SIGMAR1 | |
| SCHEMBL9844505 | 0.91 | SIGMAR1 (0.80) | SIGMAR1 | |
| SCHEMBL9844324 | 0.91 | SIGMAR1 (0.76) | SIGMAR1GRM2 | |
| SCHEMBL9844410 | 0.89 | SIGMAR1 (0.81) | SIGMAR1GRM2 | |
| SCHEMBL9677099 | 0.89 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL9844495 | 0.87 | SIGMAR1 (0.61) | SIGMAR1ALDH1A1 | |
| SCHEMBL9844061 | 0.85 | SIGMAR1 (0.83) | SIGMAR1 | |
| SCHEMBL9844376 | 0.85 | SIGMAR1 (0.83) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |