Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | DPP4 | P27487 | 4/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1027107 | 0.81 | POLB (0.66) | POLBL3MBTL1DPP4DPP8CHRM2 | |
| SCHEMBL15808498 | 0.81 | POLB (0.66) | POLBL3MBTL1DPP4DPP8CHRM2 | |
| SCHEMBL19423712 | 0.81 | POLB (0.66) | POLBL3MBTL1DPP4DPP8CHRM2 | |
| SCHEMBL20123392 | 0.81 | POLB (0.70) | POLBL3MBTL1DPP4DPP8CHRM2 | |
| SCHEMBL2779194 | 0.81 | POLB (0.70) | POLBL3MBTL1DPP4DPP8CHRM2 | |
| SCHEMBL3431498 | 0.81 | POLB (0.70) | POLBL3MBTL1DPP4DPP8CHRM2 | |
| SCHEMBL16561742 | 0.81 | POLB (0.70) | POLBL3MBTL1DPP4DPP8CHRM2 | |
| SCHEMBL5046483 | 0.81 | POLB (0.70) | POLBL3MBTL1DPP4DPP8CHRM2 | |
| SCHEMBL1712666 | 0.81 | POLB (0.70) | POLBL3MBTL1DPP4DPP8CHRM2 | |
| Hydrochloric Acid SCHEMBL19410049 | 0.80 | POLB (0.63) | POLBL3MBTL1DPP4DPP8CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | claimed |