Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | DPP4 | P27487 | 3/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16561742 | 1.00 | POLB (0.70) | POLBL3MBTL1DPP4DPP8MEN1 | |
| SCHEMBL2779194 | 1.00 | POLB (0.70) | POLBL3MBTL1DPP4DPP8MEN1 | |
| SCHEMBL14941549 | 0.94 | L3MBTL1 (0.62) | POLBL3MBTL1DPP4DPP8MEN1 | |
| SCHEMBL2308749 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL3130481 | 0.85 | POLB (0.50) | POLBL3MBTL1DPP4DPP8 | |
| SCHEMBL15808497 | 0.84 | POLB (0.78) | POLBL3MBTL1DPP4DPP8MEN1 | |
| SCHEMBL27889788 | 0.83 | POLB (0.76) | POLBL3MBTL1DPP4DPP8MEN1 | |
| SCHEMBL27976413 | 0.83 | POLB (0.76) | POLBL3MBTL1DPP4DPP8MEN1 | |
| SCHEMBL27906694 | 0.83 | POLB (0.76) | POLBL3MBTL1DPP4DPP8MEN1 | |
| SCHEMBL3966250 | 0.82 | L3MBTL1 (0.47) | POLBL3MBTL1DPP4DPP8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053495-B2 | Multi-targeted single entity conjugates | ALNYLAM PHARMACEUTICALS, INC. (US) | 2021-07-06 | — | — | US | disclosed |
| US-20180208927-A1 | MULTI-TARGETED SINGLE ENTITY CONJUGATES | ALNYLAM PHARMACEUTICALS, INC. (US) | 2018-07-26 | — | — | US | disclosed |
| EP-2620436-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2018-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053495-B2 | Multi-targeted single entity conjugates | SNRPE, DDX21, RNMT | POLB 1210/4885L3MBTL1 369/4885DPP4 2926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.