Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.51 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844078 | 0.89 | SOAT1 (0.56) | SMN1; SMN2SOAT1SOAT2KMT2AMEN1 | |
| SCHEMBL9843990 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2SOAT1 | |
| SCHEMBL9844196 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2SOAT1SOAT2KMT2AMEN1 | |
| SCHEMBL9843936 | 0.81 | SMN1; SMN2 (0.77) | SMN1; SMN2SOAT1SOAT2KMT2AMEN1 | |
| SCHEMBL6899771 | 0.81 | SOAT1 (0.62) | SMN1; SMN2SOAT1SOAT2KMT2AMEN1 | |
| SCHEMBL9463095 | 0.78 | SMN1; SMN2 (0.72) | SMN1; SMN2SOAT1SOAT2KMT2AMEN1 | |
| SCHEMBL13328398 | 0.77 | SOAT2 (0.55) | SMN1; SMN2SOAT1SOAT2KMT2AMEN1 | |
| SCHEMBL20763994 | 0.77 | SMN1; SMN2 (0.66) | SMN1; SMN2SOAT1SOAT2KMT2AMEN1 | |
| SCHEMBL6731930 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2SOAT1SOAT2KMT2AMEN1 | |
| SCHEMBL2148218 | 0.77 | SMN1; SMN2 (0.70) | SMN1; SMN2SOAT1SOAT2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | claimed |