Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.44 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2147650 | 0.85 | KMT2A (0.65) | MEN1KMT2ASMN1; SMN2SOAT1SOAT2 | |
| SCHEMBL9844053 | 0.84 | KMT2A (0.50) | MEN1KMT2ASMN1; SMN2SOAT1SOAT2 | |
| SCHEMBL9843942 | 0.83 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2SOAT1SOAT2 | |
| SCHEMBL3308654 | 0.82 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2SOAT1SOAT2 | |
| SCHEMBL9843954 | 0.77 | SOAT1 (0.47) | MEN1KMT2ASMN1; SMN2SOAT1SOAT2 | |
| SCHEMBL6899771 | 0.73 | SOAT1 (0.62) | MEN1KMT2ASMN1; SMN2SOAT1SOAT2 | |
| SCHEMBL9843936 | 0.71 | SMN1; SMN2 (0.77) | MEN1KMT2ASMN1; SMN2SOAT1SOAT2 | |
| SCHEMBL9844078 | 0.68 | SOAT1 (0.56) | MEN1KMT2ASMN1; SMN2SOAT1SOAT2 | |
| SCHEMBL9844128 | 0.68 | SOAT1 (0.55) | MEN1KMT2ASMN1; SMN2SOAT1SOAT2 | |
| SCHEMBL13328398 | 0.68 | SOAT2 (0.55) | MEN1KMT2ASMN1; SMN2SOAT1SOAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433662-A2 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-26 | — | — | EP | claimed |