Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.64 |
| ▸ | DRD2 | P14416 | 11/20 | 0.56 |
| ▸ | DRD3 | P35462 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.52 |
| ▸ | DRD1 | P21728 | 3/20 | 0.52 |
| ▸ | DRD5 | P21918 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.52 |
| ▸ | HTR7 | P34969 | 3/20 | 0.52 |
| ▸ | HRH1 | P35367 | 3/20 | 0.52 |
| ▸ | HTR2B | P41595 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.52 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844417 | 1.00 | SIGMAR1 (0.64) | SIGMAR1DRD2DRD3LMNAHTR1A | |
| SCHEMBL9844040 | 0.95 | SIGMAR1 (0.69) | SIGMAR1 | |
| SCHEMBL9844272 | 0.95 | SIGMAR1 (0.69) | SIGMAR1 | |
| SCHEMBL9844231 | 0.90 | SIGMAR1 (0.63) | SIGMAR1DRD2OPRM1 | |
| SCHEMBL9844106 | 0.90 | SIGMAR1 (0.63) | SIGMAR1DRD2 | |
| SCHEMBL9844261 | 0.90 | SIGMAR1 (0.63) | SIGMAR1DRD2 | |
| SCHEMBL9677462 | 0.90 | SIGMAR1 (0.77) | SIGMAR1 | |
| SCHEMBL9844264 | 0.90 | SIGMAR1 (0.63) | SIGMAR1DRD2OPRM1 | |
| SCHEMBL9676228 | 0.90 | SIGMAR1 (0.77) | SIGMAR1 | |
| SCHEMBL9844376 | 0.88 | SIGMAR1 (0.83) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |