SCHEMBL9844407

SCHEMBL9844407

Cc1csc(-c2nc[nH]n2)c1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 2/20 0.35
KDM5B Q9UGL1 1/20 0.35
CHEK1 O14757 1/20 0.32
SLC6A7 Q99884 1/20 0.32
GRIN2B Q13224 2/20 0.30
GRIN1 Q05586 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9844399 0.79 TDP2 (0.33) TDP2
SCHEMBL9773308 0.70 DAO (0.44) TDP2KDM5BCHEK1SLC6A7GRIN2B
SCHEMBL11996675 0.69 NPC1 (0.36)
SCHEMBL15489054 0.68 AOC3 (0.35)
SCHEMBL3730275 0.67 KDM4E (0.42) CHEK1
SCHEMBL27546488 0.67 PARP1 (0.38)
SCHEMBL11840289 0.67 GRIN1 (0.36) TDP2KDM5BSLC6A7GRIN2BGRIN1
SCHEMBL2053516 0.67 CHEK1 (0.35) TDP2KDM5BCHEK1
SCHEMBL10989579 0.66 KDM5B (0.40) TDP2KDM5B
SCHEMBL10867090 0.66 TDP2 (0.38) TDP2KDM5BSLC6A7GRIN2BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0441718-A1 Herbicidally active triazolopyridine compounds RHONE-POULENC AGROCHIMIE (FR) 1991-08-14 EP disclosed