SCHEMBL9844463

SCHEMBL9844463

O=C(CCS(=O)(=O)O)C(=O)CS(=O)(=O)O

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.38
PDE4A P27815 1/20 0.38
LMNA P02545 1/20 0.38
SLC6A6 P31641 1/20 0.38
CYP2C19 P33261 1/20 0.38
BLM P54132 1/20 0.38
APP P05067 1/20 0.35
APEX1 P27695 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL513632 0.75
SCHEMBL27821671 0.71 PTGS1 (0.45) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL3563111 0.70 FFAR3 (0.43) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL9511691 0.70 TDP1 (0.33)
SCHEMBL536402 0.70 PTGS1 (0.35) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL918089 0.69 OR51E2 (0.40) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL513587 0.69
Potassium SCHEMBL9347201 0.69 PTGS1 (0.33) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL7057221 0.67 PTGS1 (0.47) PTGS1PDE4ALMNASLC6A6CYP2C19
SCHEMBL7019166 0.67 PTGS1 (0.32) PTGS1PDE4ALMNASLC6A6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0419795-A1 2,4-pentanedione-1,5-disulfonic acid and method for preparing the same ATOCHEM NORTH AMERICA, INC. (US) 1991-04-03 EP claimed
EP-0419795-A1 2,4-pentanedione-1,5-disulfonic acid and method for preparing the same ATOCHEM NORTH AMERICA, INC. (US) 1991-04-03 EP disclosed