Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SETD7 | Q8WTS6 | 4/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844283 | 0.92 | CYP3A4 (0.58) | CYP3A4HTTSETD7CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL9844493 | 0.91 | CYP3A4 (0.57) | CYP3A4HTTSETD7CYP2D6CYP2C19 | |
| SCHEMBL9844522 | 0.91 | CYP3A4 (0.57) | CYP3A4HTTSETD7CYP2D6CYP2C19 | |
| SCHEMBL7682329 | 0.85 | FNTA (0.57) | CYP3A4HTTSETD7CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL7679240 | 0.84 | FNTA (0.56) | CYP3A4HTTSETD7CYP2D6CYP2C19 | |
| SCHEMBL9718792 | 0.83 | SETD7 (0.58) | CYP3A4HTTSETD7CYP2D6CYP2C19 | |
| SCHEMBL9718762 | 0.82 | SETD7 (0.61) | CYP3A4HTTSETD7CYP2D6CYP2C19 | |
| SCHEMBL7676763 | 0.78 | FNTA (0.55) | CYP3A4HTTSETD7CYP2D6CYP2C19 | |
| SCHEMBL9844279 | 0.78 | FNTA (0.54) | CYP3A4HTTSETD7CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL9844228 | 0.78 | FNTA (0.54) | CYP3A4HTTSETD7CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0451772-A1 | Piperidine compounds, method for preparation thereof, and a pharamceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-16 | — | — | EP | claimed |
| EP-0451772-A1 | Piperidine compounds, method for preparation thereof, and a pharamceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-16 | — | — | EP | disclosed |