Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793451 | 0.90 | S100B (0.59) | S100BALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL11114625 | 0.90 | S100B (0.59) | S100BALDH1A1CYP3A4TDP1TSHR | |
| Hydrochloric Acid SCHEMBL11575193 | 0.89 | S100B (0.57) | S100BALDH1A1CYP3A4TDP1TSHR | |
| Sulfuric Acid SCHEMBL11125865 | 0.86 | S100B (0.51) | S100BALDH1A1CYP3A4TDP1TSHR | |
| Sulfuric Acid SCHEMBL2931812 | 0.86 | S100B (0.51) | S100BALDH1A1CYP3A4TDP1TSHR | |
| Sulfuric Acid SCHEMBL10408807 | 0.85 | S100B (0.50) | S100BALDH1A1CYP3A4TDP1TSHR | |
| Nitric Acid SCHEMBL9639344 | 0.82 | S100B (0.42) | S100BALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL8766774 | 0.79 | S100B (0.43) | S100BALDH1A1TDP1IGLV6-57MAPT | |
| SCHEMBL14611743 | 0.79 | S100B (0.51) | S100BALDH1A1CYP3A4TDP1TSHR | |
| SCHEMBL10798964 | 0.78 | S100B (0.62) | S100BALDH1A1CYP3A4TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421426-A1 | Light-sensitive silver halide photographic material, silver halide emulsion, and process for preparing these | KONICA CORPORATION (JP) | 1991-04-10 | — | — | EP | disclosed |