Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3405625 | 0.80 | TAAR1 (0.57) | SLC6A4MAOASLC6A2SLC6A3FAAH | |
| SCHEMBL7560499 | 0.78 | SLC6A4 (0.48) | SLC6A4MAOASLC6A2SLC6A3FAAH | |
| SCHEMBL6560714 | 0.78 | SLC6A4 (0.59) | SLC6A4MAOASLC6A2SLC6A3 | |
| SCHEMBL30815764 | 0.74 | SLC6A4 (0.46) | SLC6A4MAOASLC6A2SLC6A3FAAH | |
| SCHEMBL14392578 | 0.74 | SLC6A4 (0.46) | SLC6A4MAOASLC6A2SLC6A3FAAH | |
| SCHEMBL7557160 | 0.74 | SLC6A4 (0.53) | SLC6A4MAOASLC6A2SLC6A3NOS3 | |
| SCHEMBL19828349 | 0.73 | SLC6A4 (0.44) | SLC6A4MAOASLC6A2SLC6A3FAAH | |
| SCHEMBL2015502 | 0.73 | SLC6A4 (0.44) | SLC6A4MAOASLC6A2SLC6A3FAAH | |
| SCHEMBL11382547 | 0.73 | SLC6A4 (0.44) | SLC6A4MAOASLC6A2SLC6A3FAAH | |
| SCHEMBL1034372 | 0.73 | KDM4E (0.63) | SLC6A4SLC6A2SLC6A3FAAHKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405104-A1 | Process for preparing antibacterial compounds and intermediates thereto | SCHERING CORPORATION (US) | 1991-01-02 | — | — | EP | disclosed |