Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 13/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1607138 | 0.83 | LMNA (0.75) | LMNASLC6A2SLC6A3PGR | |
| SCHEMBL7560499 | 0.83 | SLC6A4 (0.48) | SLC6A4MAOASLC6A2SLC6A3 | |
| SCHEMBL3405625 | 0.81 | TAAR1 (0.57) | SLC6A4LMNAMAOASLC6A2SLC6A3 | |
| SCHEMBL14392578 | 0.79 | SLC6A4 (0.46) | SLC6A4MAOASLC6A2SLC6A3TAS1R3 | |
| SCHEMBL30815764 | 0.79 | SLC6A4 (0.46) | SLC6A4MAOASLC6A2SLC6A3TAS1R3 | |
| SCHEMBL9844565 | 0.78 | SLC6A4 (0.53) | SLC6A4MAOASLC6A2SLC6A3 | |
| SCHEMBL2015502 | 0.78 | SLC6A4 (0.44) | SLC6A4MAOASLC6A2SLC6A3 | |
| SCHEMBL19828349 | 0.78 | SLC6A4 (0.44) | SLC6A4MAOASLC6A2SLC6A3TAS1R3 | |
| SCHEMBL11382547 | 0.78 | SLC6A4 (0.44) | SLC6A4MAOASLC6A2SLC6A3TAS1R3 | |
| SCHEMBL1034372 | 0.78 | KDM4E (0.63) | SLC6A4LMNASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050531-B1 | Pyridine and piperidine derivatives for treating neurodegenerative diseases | SERVIER LAB (FR) | 2004-11-17 | — | — | EP | disclosed |
| EP-1050531-A1 | Pyridine and piperidine derivatives for treating neurodegenerative diseases | ADIR ET COMPAGNIE (FR) | 2000-11-08 | — | — | EP | disclosed |