Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | SQLE | Q14534 | 3/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23036813 | 0.88 | ALDH1A1 (0.66) | ALDH1A1ALOX15PTPN1SQLETRPV1 | |
| SCHEMBL23036807 | 0.88 | ALDH1A1 (0.66) | ALDH1A1ALOX15PTPN1SQLETRPV1 | |
| SCHEMBL23036788 | 0.88 | ALDH1A1 (0.66) | ALDH1A1ALOX15PTPN1SQLETRPV1 | |
| SCHEMBL10929669 | 0.84 | ALDH1A1 (0.61) | ALDH1A1ALOX15PTPN1TRPV1FNTA | |
| SCHEMBL10929662 | 0.84 | ALDH1A1 (0.61) | ALDH1A1ALOX15PTPN1TRPV1FNTA | |
| SCHEMBL5150363 | 0.84 | ALDH1A1 (0.61) | ALDH1A1ALOX15PTPN1TRPV1FNTA | |
| SCHEMBL5150357 | 0.84 | ALDH1A1 (0.61) | ALDH1A1ALOX15PTPN1TRPV1FNTA | |
| SCHEMBL23668542 | 0.82 | ALDH1A1 (0.59) | ALDH1A1ALOX15PTPN1TRPV1FNTA | |
| SCHEMBL9844659 | 0.82 | ALDH1A1 (0.59) | ALDH1A1ALOX15PTPN1TRPV1FNTA | |
| SCHEMBL28502149 | 0.82 | ALDH1A1 (0.59) | ALDH1A1ALOX15PTPN1TRPV1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410244-A1 | Leukotriene antagonists | BAYER AG (DE) | 1991-01-30 | — | — | EP | disclosed |