Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | EP300 | Q09472 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844938 | 1.00 | PTPN1 (0.41) | PTPN1RETALDH1A1EP300TP53 | |
| SCHEMBL22677981 | 0.79 | SRC (0.55) | EGFRSRCKDR | |
| SCHEMBL29407781 | 0.79 | SRC (0.55) | EGFRSRCKDR | |
| SCHEMBL13004526 | 0.79 | RPS6KA3 (0.51) | RETALDH1A1TP53SRCRPS6KA3 | |
| SCHEMBL9844770 | 0.76 | EP300 (0.49) | RETALDH1A1EP300TP53EGFR | |
| SCHEMBL9844771 | 0.76 | NPC1 (0.43) | ALDH1A1TP53NPC1RAB9AMAPT | |
| SCHEMBL14114544 | 0.74 | MAP3K7 (0.39) | RETEGFRSRCKDRRPS6KA3 | |
| SCHEMBL13004542 | 0.74 | MAP3K7 (0.41) | RPS6KA3 | |
| SCHEMBL16939051 | 0.73 | EIF2AK3 (0.36) | RETEGFRSRCKDR | |
| SCHEMBL16939048 | 0.72 | ADORA2A (0.41) | RETEGFRSRCKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438261-A2 | Condensed heterocyclic glutamic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-24 | — | — | EP | disclosed |