Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 7/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844766 | 0.87 | KDR (0.46) | EP300RETEGFRSRCKDR | |
| SCHEMBL29407781 | 0.79 | SRC (0.55) | EGFRSRCKDR | |
| SCHEMBL22677981 | 0.79 | SRC (0.55) | EGFRSRCKDR | |
| SCHEMBL9844757 | 0.78 | DHFR (0.55) | — | |
| SCHEMBL9844769 | 0.76 | DHFR (0.43) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9844775 | 0.76 | DHFR (0.43) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9844937 | 0.76 | PTPN1 (0.41) | EP300TP53ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9844938 | 0.76 | PTPN1 (0.41) | EP300TP53ALDH1A1HPGDHSD17B10 | |
| SCHEMBL14647492 | 0.72 | ADORA2A (0.43) | — | |
| SCHEMBL8982447 | 0.72 | CYP4A11 (0.48) | EP300TP53ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0438261-A2 | Condensed heterocyclic glutamic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-24 | — | — | EP | claimed |
| EP-0438261-A2 | Condensed heterocyclic glutamic acid derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-07-24 | — | — | EP | disclosed |