Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | TOP2A | P11388 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CASP9 | P55211 | 1/20 | 0.45 |
| ▸ | BAX | Q07812 | 1/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL9692482 | 0.87 | KDM4E (0.69) | KDM4EALDH1A1LMNATOP2BHPGD | |
| SCHEMBL9690799 | 0.86 | KDM4E (0.74) | KDM4EALDH1A1LMNATOP2BHPGD | |
| Hydrochloric Acid SCHEMBL9692578 | 0.85 | KDM4E (0.73) | KDM4EALDH1A1LMNATOP2BHPGD | |
| SCHEMBL9844994 | 0.83 | KCNH2 (0.44) | KDM4EALDH1A1TOP2BHPGDHSD17B10 | |
| SCHEMBL9757225 | 0.80 | KDM4E (0.47) | KDM4EALDH1A1LMNATOP2BHPGD | |
| SCHEMBL9500971 | 0.77 | KDM4E (0.81) | KDM4EALDH1A1LMNATOP2BHPGD | |
| SCHEMBL13923333 | 0.76 | KDM4E (0.79) | KDM4EALDH1A1LMNATOP2BHPGD | |
| SCHEMBL8983611 | 0.75 | KDM4E (0.78) | KDM4EALDH1A1LMNATOP2BHPGD | |
| SCHEMBL9844999 | 0.75 | ALDH1A1 (0.68) | KDM4EALDH1A1LMNATOP2BHPGD | |
| Hydrochloric Acid SCHEMBL9693027 | 0.74 | ALDH1A1 (0.67) | KDM4EALDH1A1LMNATOP2BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0424850-A1 | Quinolone compounds and a process for their preparation | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1991-05-02 | — | — | EP | disclosed |