Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845010 | 1.00 | GSR (0.41) | GSRSLC1A1GRM8GRM6GRIN2D | |
| SCHEMBL9845084 | 0.81 | GSR (0.43) | GSRSLC1A1GRM8GRM6GRIN2D | |
| SCHEMBL9845087 | 0.81 | GSR (0.43) | GSRSLC1A1GRM8GRM6GRIN2D | |
| SCHEMBL9334907 | 0.76 | GSR (0.39) | GSRSLC1A1GRM8GRM6GRIN2D | |
| SCHEMBL12189856 | 0.76 | GSR (0.50) | GSRSLC1A1GRM8GRM6GRIN2D | |
| SCHEMBL21531606 | 0.73 | SLC1A1 (0.48) | GSRSLC1A1GRM8GRM6GRIN2D | |
| SCHEMBL4289326 | 0.73 | NOS3 (0.49) | GSRSLC1A1GRM8GRM6GRIN2D | |
| SCHEMBL302495 | 0.72 | NOS3 (0.51) | GSRSLC1A1GRM8GRM6GRIN2D | |
| SCHEMBL1512959 | 0.72 | GSR (0.46) | GSRSLC1A1GRM8GRM6GRIN2D | |
| SCHEMBL31480708 | 0.72 | GSR (0.46) | GSRSLC1A1GRM8GRM6GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446699-A1 | Inhibitors of nitric oxide biosynthesis | MERRELL PHARMACEUTICALS INC. (US) | 1991-09-18 | — | — | EP | disclosed |