Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTC | P00480 | 1/20 | 0.49 |
| ▸ | DDAH1 | O94760 | 4/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 3/20 | 0.41 |
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | ARG2 | P78540 | 4/20 | 0.39 |
| ▸ | ARG1 | P05089 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845012 | 1.00 | OTC (0.49) | OTCDDAH1GSRNOS2NOS1 | |
| Hydrochloric Acid SCHEMBL8472038 | 0.98 | OTC (0.48) | OTCDDAH1GSRNOS2NOS1 | |
| Hydrochloric Acid SCHEMBL8472273 | 0.94 | GSR (0.43) | OTCDDAH1GSRNOS2NOS1 | |
| SCHEMBL2238409 | 0.83 | OTC (0.51) | OTCDDAH1GSRNOS2ARG2 | |
| SCHEMBL2238416 | 0.83 | OTC (0.51) | OTCDDAH1GSRNOS2ARG2 | |
| Arginine SCHEMBL28224381 | 0.83 | OTC (0.46) | OTCDDAH1GSRNOS2NOS1 | |
| SCHEMBL16615729 | 0.79 | GSR (0.47) | OTCDDAH1GSRARG2ARG1 | |
| SCHEMBL7597963 | 0.78 | OTC (0.47) | OTCDDAH1GSRNOS2NOS1 | |
| SCHEMBL9845064 | 0.78 | OTC (0.47) | OTCDDAH1GSRNOS2NOS1 | |
| Arginine SCHEMBL6374054 | 0.78 | OTC (0.56) | OTCDDAH1GSRNOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446699-A1 | Inhibitors of nitric oxide biosynthesis | MERRELL PHARMACEUTICALS INC. (US) | 1991-09-18 | — | — | EP | disclosed |