Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | TPMT | P51580 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27747073 | 0.88 | ALDH1A1 (0.56) | CA12CA1CA2CA4CA6 | |
| SCHEMBL25406539 | 0.87 | CA12 (0.46) | CA12CA1CA2CA4CA6 | |
| SCHEMBL6933447 | 0.83 | ESR1 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1554712 | 0.81 | CA12 (0.71) | CA12CA1CA2CA4CA6 | |
| SCHEMBL966378 | 0.78 | CA12 (0.71) | CA12CA1CA2CA4CA6 | |
| SCHEMBL1538088 | 0.78 | CA12 (0.43) | CA12CA1CA2CA4CA6 | |
| SCHEMBL10337047 | 0.77 | KDM4E (0.58) | ALDH1A1TSHRKDM4EHTTKMT2A | |
| SCHEMBL1134227 | 0.77 | KDM4E (0.58) | ALDH1A1TSHRKDM4EHTTKMT2A | |
| Hydrochloric Acid SCHEMBL17667160 | 0.77 | CA12 (0.69) | CA12CA1CA2CA4CA6 | |
| SCHEMBL10453887 | 0.76 | KMT2A (0.63) | CA12CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59018727-A | — | — | None | — | — | JP | disclosed |
| EP-0416288-A2 | Reduction of acidity of polyesters by melt reaction endcapping | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0414009-A2 | Reduction of acidity of polyesters by melt reaction endcapping with dialkyloxalate | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-02-27 | — | — | EP | disclosed |
| EP-0414008-A2 | Reduction of acidity of polyesters by melt reaction endcapping with enamines or schiff bases | BRIDGESTONE/FIRESTONE, INC. (US) | 1991-02-27 | — | — | EP | disclosed |
| JP-S5918727-A | METHOD FOR DISPERSING SYNTHETIC PARTICLE FOR POLYESTER | TORAY IND INC | 1984-01-31 | — | — | JP | disclosed |