Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 4/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PDE1A | P54750 | 2/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845193 | 0.91 | GAA (0.59) | ALDH1A1GAAKMT2APNPPDE4A | |
| SCHEMBL27277482 | 0.88 | ALDH1A1 (0.52) | ALDH1A1GAAKMT2APNPPDE4A | |
| SCHEMBL5054173 | 0.84 | PNP (0.54) | ALDH1A1GAAKMT2APNPPDE4A | |
| SCHEMBL7416953 | 0.84 | ALDH1A1 (0.47) | ALDH1A1GAAKMT2APNPKDM4E | |
| SCHEMBL7419700 | 0.80 | ALDH1A1 (0.46) | ALDH1A1GAAKMT2APNPKDM4E | |
| SCHEMBL15290224 | 0.79 | ALDH1A1 (0.56) | ALDH1A1GAAKMT2APNPPDE4A | |
| SCHEMBL5431750 | 0.79 | GAA (0.48) | ALDH1A1GAAKMT2APNPPDE4A | |
| SCHEMBL6233163 | 0.76 | PNP (0.58) | ALDH1A1GAAKMT2APNPPDE4A | |
| SCHEMBL27627950 | 0.75 | ALDH1A1 (0.60) | ALDH1A1GAAKMT2APNPADORA2A | |
| SCHEMBL11661807 | 0.74 | PNP (0.62) | ALDH1A1GAAKMT2APNPPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417790-A2 | S-triazolo[3,4-i]purine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-03-20 | — | — | EP | disclosed |