Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11001848 | 0.88 | TDP1 (0.50) | ARTDP1PRKCAGAAALDH1A1 | |
| SCHEMBL5025539 | 0.87 | ADRA1D (0.44) | ARTDP1PRKCAALDH1A1LMNA | |
| Triacetin SCHEMBL19859036 | 0.86 | AR (0.50) | ARTDP1PRKCAGAAALDH1A1 | |
| Triacetin SCHEMBL3870 | 0.85 | TDP1 (0.56) | ARTDP1PRKCAGAAALDH1A1 | |
| Triacetin SCHEMBL821340 | 0.85 | TDP1 (0.56) | ARTDP1PRKCAGAAALDH1A1 | |
| SCHEMBL28558230 | 0.84 | AR (0.42) | ARTDP1PRKCALMNAMEN1 | |
| Triacetin SCHEMBL31035933 | 0.83 | TDP1 (0.54) | ARTDP1PRKCAGAAALDH1A1 | |
| Triacetin SCHEMBL31301065 | 0.83 | TDP1 (0.54) | ARTDP1PRKCAGAAALDH1A1 | |
| Triacetin SCHEMBL16446056 | 0.83 | TDP1 (0.54) | ARTDP1PRKCAGAAALDH1A1 | |
| Triacetin SCHEMBL4367394 | 0.83 | TDP1 (0.54) | ARTDP1PRKCAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452680-A1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |