Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28810886 | 0.84 | CYP2C19 (0.59) | CYP2C19HIF1AMAPTKMT2AKIF11 | |
| SCHEMBL1604732 | 0.80 | CYP2C19 (0.59) | CYP2C19HIF1AMAPTKMT2AKIF11 | |
| SCHEMBL2170468 | 0.76 | KCNN4 (0.48) | CYP2C19HIF1AKCNN4CYP1A2ALDH1A1 | |
| SCHEMBL9845388 | 0.76 | CYP2C19 (0.39) | CYP2C19HIF1AKIF11DRD2OPRM1 | |
| SCHEMBL1537402 | 0.76 | CYP2C19 (0.53) | CYP2C19HIF1AMAPTKMT2AKIF11 | |
| SCHEMBL9409973 | 0.75 | CYP2C19 (0.47) | CYP2C19HIF1AMAPTKMT2AKIF11 | |
| SCHEMBL11074278 | 0.74 | CYP2C19 (0.43) | CYP2C19HIF1AMAPTKMT2AKIF11 | |
| SCHEMBL27649423 | 0.74 | KCNN4 (0.46) | CYP2C19HIF1AKCNN4CYP1A2ALDH1A1 | |
| SCHEMBL8483276 | 0.73 | HIF1A (0.46) | CYP2C19HIF1AMAPTKMT2AKIF11 | |
| SCHEMBL1011933 | 0.73 | KCNN4 (0.41) | CYP2C19HIF1AMAPTKMT2AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420266-A2 | Chromene or thiochromene derivatives, process for preparing the same, intermediate therefor, pharmaceutical compositions containing said derivatives and the use of said derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1991-04-03 | — | — | EP | disclosed |