Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170468 | 0.79 | KCNN4 (0.48) | CYP2C19HIF1AKCNN4ALDH1A1TAAR1 | |
| SCHEMBL28810886 | 0.79 | CYP2C19 (0.59) | CYP2C19HIF1AKCNN4ALDH1A1GRIN1 | |
| SCHEMBL27649423 | 0.77 | KCNN4 (0.46) | CYP2C19HIF1AKCNN4ALDH1A1TAAR1 | |
| SCHEMBL9845386 | 0.76 | CYP2C19 (0.46) | CYP2C19HIF1AKCNN4ALDH1A1GRIN1 | |
| SCHEMBL1011933 | 0.76 | KCNN4 (0.41) | CYP2C19HIF1AKCNN4ALDH1A1TAAR1 | |
| SCHEMBL915727 | 0.76 | KCNN4 (0.41) | CYP2C19HIF1AKCNN4ALDH1A1TAAR1 | |
| SCHEMBL1604732 | 0.75 | CYP2C19 (0.59) | CYP2C19HIF1AKCNN4ALDH1A1GRIN1 | |
| SCHEMBL3321479 | 0.75 | MAOA (0.40) | CYP2C19HIF1AKCNN4ALDH1A1 | |
| SCHEMBL29077389 | 0.74 | TAAR1 (0.52) | CYP2C19HIF1AKCNN4ALDH1A1TAAR1 | |
| SCHEMBL1537405 | 0.74 | CYP2C19 (0.47) | CYP2C19HIF1AKCNN4ALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420266-A2 | Chromene or thiochromene derivatives, process for preparing the same, intermediate therefor, pharmaceutical compositions containing said derivatives and the use of said derivatives | TANABE SEIYAKU CO., LTD. (JP) | 1991-04-03 | — | — | EP | disclosed |