SCHEMBL9845491

SCHEMBL9845491

C[SiH2]N=C=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18920734 0.67
SCHEMBL27909439 0.67
SCHEMBL18009697 0.62
Benzene SCHEMBL28224994 0.56 ALDH1A1 (0.75)
Methylisothiocyanate SCHEMBL27880816 0.56
Methylisothiocyanate SCHEMBL3152 0.56
Methylisothiocyanate SCHEMBL28258797 0.53
Methylisothiocyanate SCHEMBL29112077 0.53
SCHEMBL28777937 0.49
SCHEMBL31265539 0.48

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0412939-A2 Certain benzopyran and benzothiopyran derivatives CIBA-GEIGY AG (CH) 1991-02-13 EP disclosed
EP-0217634-A2 Sequencing of peptides Beckman Research Institute of the City of Hope (US) 1987-04-08 EP disclosed