Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6630020 | 0.80 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL9547230 | 0.79 | — | — | |
| SCHEMBL2973493 | 0.71 | — | — | |
| SCHEMBL2975726 | 0.70 | — | — | |
| SCHEMBL16711947 | 0.69 | — | — | |
| SCHEMBL4028237 | 0.68 | — | — | |
| SCHEMBL3944984 | 0.67 | — | — | |
| SCHEMBL3944983 | 0.67 | — | — | |
| SCHEMBL19558045 | 0.67 | — | — | |
| SCHEMBL6627084 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418143-A1 | Dicarboxylic acids derivatives containing a nitrogen or oxygen heteroring, process for their preparation and their use as medicines | ROUSSEL-UCLAF (FR) | 1991-03-20 | — | — | EP | disclosed |