SCHEMBL9845815

SCHEMBL9845815

C=Cc1cc(C)ccc1CCl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
SRC P12931 1/20 0.40
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 4/20 0.33
MAPT P10636 4/20 0.33
POLB P06746 2/20 0.33
HPGD P15428 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GPR55 Q9Y2T6 2/20 0.31
CYP1A2 P05177 2/20 0.31
CYP2A6 P11509 2/20 0.31
TAAR1 Q96RJ0 1/20 0.31
THRB P10828 1/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL810252 0.84 NPSR1 (0.43) KMT2ANPSR1SRCTP53TDP1
SCHEMBL29700765 0.82 SRC (0.44) SRCTP53TDP1ALDH1A1MAPT
SCHEMBL9468752 0.82 SRC (0.44) SRCTP53TDP1ALDH1A1MAPT
SCHEMBL809732 0.80 KMT2A (0.38) KMT2ANPSR1SRCTP53TDP1
SCHEMBL9156512 0.80 SRC (0.40) SRCTP53TDP1ALDH1A1MAPT
SCHEMBL16953613 0.78 SRC (0.39) KMT2ASRCTP53TDP1ALDH1A1
SCHEMBL19295961 0.77 KDM4E (0.41) SRCTP53TDP1ALDH1A1MAPT
SCHEMBL27519811 0.77 SRC (0.38) SRCTP53TDP1ALDH1A1MAPT
SCHEMBL19142861 0.74 TAAR1 (0.37) KMT2ANPSR1SRCTP53TDP1
SCHEMBL9296438 0.73 ALDH1A1 (0.31) KMT2ANPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0036528-B1 BUTADIENE-STYRENE-VINYL BENZYL CHLORIDE TERPOLYMERS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1985-01-16 EP claimed
EP-0415729-A2 Vinylphenyl compound, process for the production thereof, polymerizable composition containing same, and crosslinked polymer formed therefrom TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1991-03-06 EP disclosed
EP-0036528-B1 BUTADIENE-STYRENE-VINYL BENZYL CHLORIDE TERPOLYMERS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1985-01-16 EP disclosed
EP-0036528-A1 Butadiene-styrene-vinyl benzyl chloride terpolymers THE FIRESTONE TIRE & RUBBER COMPANY (US) 1981-09-30 EP disclosed
US-4268642-A Butadiene-styrene-vinyl benzyl chloride terpolymers THE FIRESTONE TIRE & RUBBER COMPANY (US) 1981-05-19 US disclosed