Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14034153 | 0.77 | MAPT (0.41) | CYP3A4CYP2D6MAPTSLC6A2TAAR1 | |
| SCHEMBL8545241 | 0.77 | MAPT (0.41) | CYP3A4CYP2D6MAPTSLC6A2TAAR1 | |
| SCHEMBL15944879 | 0.77 | MAPT (0.41) | CYP3A4CYP2D6MAPTSLC6A2TAAR1 | |
| SCHEMBL5712498 | 0.75 | MAPT (0.40) | ATMCYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL5712499 | 0.75 | MAPT (0.40) | ATMCYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL15264183 | 0.71 | MAPT (0.39) | CYP3A4CYP2D6MAPTSLC6A2TAAR1 | |
| SCHEMBL15264184 | 0.71 | MAPT (0.39) | CYP3A4CYP2D6MAPTSLC6A2TAAR1 | |
| SCHEMBL27393645 | 0.70 | MAPT (0.41) | CYP3A4MAPTALDH1A1KDM4ETHRB | |
| SCHEMBL7764876 | 0.69 | CYP3A4 (0.47) | CYP3A4CYP2D6MAPTSLC6A2TAAR1 | |
| SCHEMBL7764872 | 0.69 | CYP3A4 (0.47) | CYP3A4CYP2D6MAPTSLC6A2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430556-A2 | (1-Akylsubstituted) and 1,1-dialkylsubstituted) carbacephalosporins | ELI LILLY AND COMPANY (US) | 1991-06-05 | — | — | EP | disclosed |