Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764876 | 1.00 | CYP3A4 (0.47) | CYP3A4CYP2D6CYP1A2PRMT1ALDH1A1 | |
| SCHEMBL7764925 | 0.89 | LTA4H (0.45) | CYP3A4CYP2D6CYP1A2PRMT1ALDH1A1 | |
| SCHEMBL7764929 | 0.89 | LTA4H (0.45) | CYP3A4CYP2D6CYP1A2PRMT1ALDH1A1 | |
| SCHEMBL7767444 | 0.83 | HTT (0.46) | ALDH1A1GAAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL7767447 | 0.83 | HTT (0.46) | ALDH1A1GAAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL14034153 | 0.77 | MAPT (0.41) | CYP3A4CYP2D6ALDH1A1TDP1GAA | |
| SCHEMBL8545241 | 0.77 | MAPT (0.41) | CYP3A4CYP2D6ALDH1A1TDP1GAA | |
| SCHEMBL15944879 | 0.77 | MAPT (0.41) | CYP3A4CYP2D6ALDH1A1TDP1GAA | |
| SCHEMBL7764897 | 0.74 | PPID (0.42) | CYP3A4CYP2D6CYP1A2PRMT1ALDH1A1 | |
| SCHEMBL7764894 | 0.74 | PPID (0.42) | CYP3A4CYP2D6CYP1A2PRMT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639566-B1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5461158-A | Immunodeficiency and autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0639566-A1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |