Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333881 | 0.82 | MAPT (0.35) | HCAR2L3MBTL1MAPTLMNAIDH1 | |
| SCHEMBL9246249 | 0.75 | MAPT (0.32) | MAPTRECQLKDM4EAPAF1 | |
| SCHEMBL9281981 | 0.75 | MAPT (0.37) | HCAR2MAPTLMNAIDH1RECQL | |
| SCHEMBL9846139 | 0.74 | CYP2C9 (0.37) | HCAR2MAPTNPSR1RECQLKDM4E | |
| SCHEMBL9846230 | 0.74 | BTK (0.41) | MAPTPOLBMEN1KMT2AIDH1 | |
| SCHEMBL9432629 | 0.71 | MEN1 (0.47) | MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9681299 | 0.70 | MAPT (0.35) | HCAR2MAPTPOLBLMNAIDH1 | |
| SCHEMBL9846283 | 0.70 | MAPT (0.35) | MAPTPOLBLMNAIDH1RECQL | |
| SCHEMBL9680313 | 0.70 | PDE1A (0.32) | MAPTRECQLKDM4EAPAF1 | |
| SCHEMBL9246243 | 0.70 | PDE1A (0.32) | MAPTRECQLKDM4EAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |