Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | GRM5 | P41594 | 7/20 | 0.50 |
| ▸ | CCR1 | P32246 | 3/20 | 0.49 |
| ▸ | CCR5 | P51681 | 3/20 | 0.49 |
| ▸ | CCR8 | P51685 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7142629 | 0.83 | KDM4E (0.50) | KDM4ETDP1CCR1CCR5CCR8 | |
| SCHEMBL7152644 | 0.81 | KDM4E (0.77) | KDM4ETDP1CCR1CCR5CCR8 | |
| SCHEMBL9756610 | 0.81 | GRM5 (0.60) | KDM4ETDP1GRM5CCR1CCR5 | |
| Hydrochloric Acid SCHEMBL10564300 | 0.79 | GRM5 (0.59) | KDM4ETDP1GRM5CCR1CCR5 | |
| SCHEMBL198407 | 0.77 | CCR1 (0.58) | KDM4ETDP1GRM5CCR1CCR5 | |
| SCHEMBL19047220 | 0.77 | KDM4E (0.63) | KDM4ETDP1GRM5CCR1CCR5 | |
| SCHEMBL13133534 | 0.75 | KDM4E (0.70) | KDM4ETDP1CCR1CCR5CCR8 | |
| SCHEMBL322756 | 0.74 | KDM4E (1.00) | KDM4ETDP1CCR1CCR5CCR8 | |
| SCHEMBL29354466 | 0.74 | KDM4E (1.00) | KDM4ETDP1CCR1CCR5CCR8 | |
| SCHEMBL19882071 | 0.74 | KDM4E (0.65) | KDM4ETDP1CCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431421-A2 | Heteroarylsubstituted pyridinylpyrimidin derivatives | BAYER AG (DE) | 1991-06-12 | — | — | EP | claimed |
| EP-0431421-A2 | Heteroarylsubstituted pyridinylpyrimidin derivatives | BAYER AG (DE) | 1991-06-12 | — | — | EP | disclosed |