Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.33 |
| ▸ | IDH1 | O75874 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680359 | 0.89 | MAPT (0.34) | MAPTKDM4EAPAF1RECQLGAA | |
| SCHEMBL9846298 | 0.87 | PDE3B (0.38) | MAPTKDM4EAPAF1RECQLGAA | |
| SCHEMBL9846236 | 0.83 | MAPT (0.38) | MAPTKDM4EAPAF1RECQLGAA | |
| SCHEMBL9682064 | 0.81 | MAPT (0.34) | MAPTKDM4EAPAF1RECQLGAA | |
| SCHEMBL9846283 | 0.78 | MAPT (0.35) | MAPTKDM4EAPAF1RECQLGAA | |
| SCHEMBL9846203 | 0.78 | PDE3B (0.38) | MAPTKDM4EAPAF1RECQLGAA | |
| SCHEMBL9846318 | 0.75 | MAPT (0.38) | MAPTKDM4EAPAF1RECQLGAA | |
| SCHEMBL9681421 | 0.73 | MAPT (0.37) | MAPTKDM4EAPAF1RECQLGAA | |
| SCHEMBL9681442 | 0.72 | KDM4E (0.36) | MAPTKDM4EAPAF1RECQLPDE10A | |
| SCHEMBL9681915 | 0.72 | PDE10A (0.40) | MAPTKDM4EAPAF1RECQLGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |