Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.41 |
| ▸ | TUBB | P07437 | 4/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846281 | 0.92 | SMN1; SMN2 (0.44) | SMN1; SMN2RAB9ALMNATP53HTT | |
| SCHEMBL9368188 | 0.86 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9ALMNATP53HTT | |
| SCHEMBL9372321 | 0.83 | SMN1; SMN2 (0.59) | SMN1; SMN2RAB9ALMNATP53HTT | |
| SCHEMBL9368584 | 0.80 | RAB9A (0.60) | SMN1; SMN2RAB9ALMNATP53HTT | |
| SCHEMBL2932936 | 0.79 | AKR1C3 (0.47) | SMN1; SMN2RAB9ALMNAHTTHIF1A | |
| SCHEMBL9368586 | 0.79 | RAB9A (0.63) | SMN1; SMN2RAB9ALMNATP53HTT | |
| Hydrochloric Acid SCHEMBL9368917 | 0.79 | RAB9A (0.59) | SMN1; SMN2RAB9ALMNATP53HTT | |
| Hydrochloric Acid SCHEMBL9373375 | 0.78 | RAB9A (0.62) | SMN1; SMN2RAB9ALMNATP53HTT | |
| SCHEMBL9368175 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9ALMNATP53HTT | |
| SCHEMBL9372311 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9ALMNATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419210-A1 | Novel benzimidazole compounds and their use | PFIZER INC. (US) | 1991-03-27 | — | — | EP | claimed |