SCHEMBL9846335

SCHEMBL9846335

CCCCCC(C)(C)c1ccc(Nc2ccccc2)c(C(C)(C)CCCCC)c1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 19/20 0.44
CNR1 P21554 18/20 0.44
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
GFER P55789 1/20 0.38
KMT2A Q03164 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10181058 0.92 CNR2 (0.47) CNR2CNR1
SCHEMBL502028 0.89 CNR2 (0.42) CNR2CNR1
SCHEMBL8962174 0.84 GAA (0.41) CNR2CNR1KDM4EMEN1ALDH1A1
SCHEMBL8746945 0.83 CNR2 (0.43) CNR2CNR1
SCHEMBL501783 0.81 CNR2 (0.45) CNR2CNR1
SCHEMBL501958 0.81 CNR2 (0.49) CNR2CNR1MEN1ALDH1A1GAA
SCHEMBL10699000 0.77 CNR2 (0.46) CNR2CNR1
SCHEMBL30108338 0.76 MAPT (0.46) CNR2CNR1MEN1ALDH1A1GAA
SCHEMBL9332912 0.75 CNR2 (0.49) CNR2CNR1
SCHEMBL886922 0.75 GAA (0.50) KDM4EMEN1ALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0432089-A1 Lubricating oil compositions CIBA-GEIGY AG (CH) 1991-06-12 EP disclosed