Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746945 | 0.90 | CNR2 (0.43) | CNR2CNR1 | |
| SCHEMBL15957743 | 0.85 | GAA (0.40) | GAAKCNH3MAPTMEN1KMT2A | |
| SCHEMBL9846335 | 0.84 | CNR2 (0.44) | GAAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL10453098 | 0.83 | NPC1 (0.45) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL28512706 | 0.82 | GAA (0.46) | GAAKCNH3MAPTMEN1KMT2A | |
| SCHEMBL17254861 | 0.82 | MAPT (0.44) | GAAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL8962178 | 0.80 | MAPT (0.42) | GAAKCNH3MAPTMEN1KMT2A | |
| SCHEMBL871745 | 0.80 | CDC25B (0.42) | GAAKMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL11216774 | 0.79 | CNR2 (0.43) | GAACNR2CNR1 | |
| SCHEMBL1605213 | 0.79 | KDM4E (0.42) | GAAKMT2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512950-B1 | Substituted 1-aminonaphtalenes and stabilized compositions | CIBA GEIGY AG (CH) | 1996-01-17 | — | — | EP | claimed |
| EP-0512950-A1 | Substituted 1-aminonaphtalenes and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-11 | — | — | EP | claimed |
| US-5160647-A | High temperature lubricants, heat and oxidation resistance | CIBA-GEIGY CORPORATION (US) | 1992-11-03 | — | — | US | claimed |
| EP-3214078-A1 | 3-ARYLBENZOFURANONE COMPOUND AND COMPOSITION FORMED THEREFROM | Eutec Chemical Co., Ltd. (TW) | 2017-09-06 | — | — | EP | disclosed |
| EP-0512950-B1 | Substituted 1-aminonaphtalenes and stabilized compositions | CIBA GEIGY AG (CH) | 1996-01-17 | — | — | EP | disclosed |
| US-5244953-A | Polymers, oxidation and heat resistance | CIBA-GEIGY CORPORATION (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0512950-A1 | Substituted 1-aminonaphtalenes and stabilized compositions | CIBA-GEIGY AG (CH) | 1992-11-11 | — | — | EP | disclosed |
| US-5160647-A | High temperature lubricants, heat and oxidation resistance | CIBA-GEIGY CORPORATION (US) | 1992-11-03 | — | — | US | disclosed |