Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9805017 | 0.84 | MAOA (0.43) | MAOAGRM2BRAFKDRSIRT2 | |
| SCHEMBL9846402 | 0.80 | GRM2 (0.36) | GRM2BRAFKDRTACR1 | |
| SCHEMBL3041240 | 0.77 | MAOA (0.57) | MAOAGRM2 | |
| SCHEMBL9846416 | 0.75 | GRM2 (0.41) | MAOAGRM2BRAFKDRSIRT2 | |
| SCHEMBL11748158 | 0.75 | CA1 (0.58) | MAPTSMN1; SMN2CA1CA2CA4 | |
| SCHEMBL3043511 | 0.74 | MAOA (0.48) | MAOA | |
| SCHEMBL3048358 | 0.74 | MAOA (0.59) | MAOA | |
| SCHEMBL5999012 | 0.73 | MAOA (0.50) | MAOACA1CA2CA4CA6 | |
| SCHEMBL3039861 | 0.73 | MAOA (0.58) | MAOAGRM2 | |
| SCHEMBL9846421 | 0.73 | MAOA (0.54) | MAOAGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417044-A2 | Oxazolidinones and thiones as plantgrowth regulators | CIBA-GEIGY AG (CH) | 1991-03-13 | — | — | EP | disclosed |