Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | BTK | Q06187 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.47 |
| ▸ | RELA | Q04206 | 4/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3307631 | 1.00 | GAA (0.53) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL2936974 | 1.00 | GAA (0.53) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL14249955 | 0.85 | GAA (0.49) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL14249956 | 0.85 | GAA (0.49) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL15502088 | 0.84 | GAA (0.54) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL14318900 | 0.84 | GAA (0.45) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL20464506 | 0.81 | ALDH1A1 (0.39) | GAAKMT2A | |
| SCHEMBL8225701 | 0.80 | GAA (0.54) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL18570971 | 0.80 | GAA (0.54) | GAABTKNFKB1NFKB2RELA | |
| SCHEMBL4949895 | 0.79 | GAA (0.55) | GAABTKNFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695237-A1 | NOVEL COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | F. Hoffmann-La Roche AG (CH) | 2026-02-18 | — | — | EP | disclosed |
| WO-2024213625-A1 | NOVEL COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-10-17 | — | — | WO | disclosed |
| CN-1054980-A | Optically active 8-BAY 128039 carboxylic acid derivative, their preparation method and their intermediate | KYORIN SEIYAKU KK (JP) | 1991-10-02 | — | — | CN | disclosed |
| EP-0443498-A1 | Isoindoline derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |