Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 6/20 | 0.60 |
| ▸ | HEXB | P07686 | 6/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1188681 | 0.87 | HEXA (0.51) | HEXAHEXBCYP1B1KMT2APOLB | |
| SCHEMBL9162685 | 0.81 | DYRK3 (0.55) | HEXAHEXBCYP1B1TDP1KMT2A | |
| SCHEMBL4997995 | 0.77 | HEXA (1.00) | HEXAHEXBCYP1B1KMT2APOLB | |
| SCHEMBL6278202 | 0.74 | HEXA (0.71) | HEXAHEXBCYP1B1TDP1KMT2A | |
| SCHEMBL29016056 | 0.74 | GCGR (0.38) | TDP1KMT2AMEN1 | |
| SCHEMBL2363008 | 0.73 | HEXA (0.71) | HEXAHEXBCYP1B1TDP1KMT2A | |
| SCHEMBL28697572 | 0.73 | HEXA (0.63) | HEXAHEXBCYP1B1KMT2APOLB | |
| SCHEMBL29405261 | 0.73 | HEXA (0.63) | HEXAHEXBCYP1B1KMT2APOLB | |
| SCHEMBL9627022 | 0.72 | HEXA (0.69) | HEXAHEXBCYP1B1TDP1KMT2A | |
| SCHEMBL20893694 | 0.72 | HEXA (0.69) | HEXAHEXBCYP1B1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413551-A2 | Stabilized polymeric dispersions | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-02-20 | — | — | EP | claimed |