Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21847988 | 0.80 | CFTR (0.37) | EGFRCFTRGOPCCYP2C9KMT2A | |
| SCHEMBL29133215 | 0.74 | MAOA (0.45) | EGFRCFTRGOPCCYP2C9KMT2A | |
| SCHEMBL15657386 | 0.69 | CFTR (0.45) | EGFRCFTRGOPCCYP2C9KMT2A | |
| SCHEMBL4095120 | 0.69 | MAOB (0.41) | EGFR | |
| SCHEMBL22904539 | 0.69 | CYP1A2 (0.32) | EGFRALDH1A1 | |
| SCHEMBL576510 | 0.69 | KMT2A (0.40) | EGFRCFTRGOPCCYP2C9KMT2A | |
| SCHEMBL21107945 | 0.65 | CFTR (0.35) | EGFRCFTRGOPCCYP2C9KMT2A | |
| SCHEMBL577105 | 0.64 | MEN1 (0.41) | CYP2C9KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL11469864 | 0.63 | CFTR (0.39) | CFTRGOPCCYP2C9KMT2AMEN1 | |
| SCHEMBL18981138 | 0.63 | EGFR (0.57) | EGFRCFTRGOPCCYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455909-A2 | 5-[1-(Imidazol)methyl]-3,3-disubstituted-2(3H) furanone derivatives | MARION MERRELL DOW INC. (US) | 1991-11-13 | — | — | EP | disclosed |
| US-5039691-A | Anticholinergic agents | MARION MERRELL DOW INC. (US) | 1991-08-13 | — | — | US | disclosed |