Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BCL9 | O00512 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462248 | 0.90 | HTR2A (0.51) | HTR2AALDH1A1MAPTHTTKMT2A | |
| SCHEMBL7519250 | 0.86 | HTR2A (0.55) | HTR2AALDH1A1HTTKMT2AGAA | |
| SCHEMBL29586770 | 0.86 | ALDH1A1 (0.57) | HTR2AALDH1A1MAPTHTTKMT2A | |
| SCHEMBL8445851 | 0.86 | ALDH1A1 (0.57) | HTR2AALDH1A1MAPTHTTKMT2A | |
| SCHEMBL29462425 | 0.85 | SMN1; SMN2 (0.55) | HTR2AALDH1A1MAPTHTTKMT2A | |
| SCHEMBL13324861 | 0.85 | SMN1; SMN2 (0.55) | HTR2AALDH1A1MAPTHTTKMT2A | |
| SCHEMBL5022220 | 0.83 | HTR2A (0.63) | HTR2AALDH1A1MAPTHTTKMT2A | |
| SCHEMBL13324859 | 0.82 | HTR2A (0.51) | HTR2AALDH1A1MAPTHTTKMT2A | |
| SCHEMBL7164084 | 0.81 | HTR2A (0.64) | HTR2AALDH1A1MAPTHTTKMT2A | |
| SCHEMBL6594172 | 0.81 | HTR2A (0.74) | HTR2AALDH1A1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429232-A1 | N-substituted derivatives of 3R,4R-ethyl-[(1-methyl-1H-imidazol-5-yl)methyl]-2-pyrrolidinone | ALLERGAN, INC. (US) | 1991-05-29 | — | — | EP | disclosed |