Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8016313 | 0.94 | TLR8 (0.67) | TLR8TP53CASRSMN1; SMN2ALDH1A1 | |
| SCHEMBL9847098 | 0.87 | TLR8 (0.57) | TLR8MAPTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL16486950 | 0.84 | TLR8 (1.00) | TLR8TP53 | |
| SCHEMBL28505372 | 0.80 | TLR8 (0.51) | TLR8CASRTDP1CNR2HTT | |
| SCHEMBL24744942 | 0.79 | TLR8 (0.50) | TLR8TP53CASRMAPTSMN1; SMN2 | |
| SCHEMBL31066875 | 0.78 | TLR8 (0.70) | TLR8TP53MAPTSMN1; SMN2TDP1 | |
| SCHEMBL31066882 | 0.78 | TLR8 (0.70) | TLR8TP53MAPTSMN1; SMN2TDP1 | |
| SCHEMBL17053182 | 0.78 | TLR8 (0.70) | TLR8TP53MAPTSMN1; SMN2TDP1 | |
| SCHEMBL20242949 | 0.78 | TLR8 (0.70) | TLR8TP53MAPTSMN1; SMN2TDP1 | |
| SCHEMBL9274775 | 0.78 | TLR8 (0.70) | TLR8TP53MAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428260-A2 | Metal surface treatment agents | SANWA LABORATORY LTD. (JP) | 1991-05-22 | — | — | EP | claimed |