Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCN1 | O60741 | 2/20 | 0.44 |
| ▸ | HCN4 | Q9Y3Q4 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9205898 | 0.83 | HCN1 (0.59) | HCN1HCN4CYP1A2CYP2D6TSHR | |
| Iodide SCHEMBL9004425 | 0.82 | HCN1 (0.57) | HCN1HCN4CYP1A2CYP2D6TSHR | |
| SCHEMBL9209045 | 0.80 | HCN1 (0.46) | HCN1HCN4CYP1A2CYP2D6TSHR | |
| SCHEMBL9277873 | 0.72 | TSHR (0.51) | HCN1HCN4CYP1A2CYP2D6TSHR | |
| SCHEMBL9378372 | 0.70 | HCN1 (0.46) | HCN1HCN4CYP1A2CYP2D6TSHR | |
| SCHEMBL14288498 | 0.70 | MAPT (0.37) | CYP1A2CYP2D6TSHRMAPTCRHBP | |
| SCHEMBL22870227 | 0.68 | MAPT (0.37) | CYP1A2CYP2D6TSHRMAPTCRHBP | |
| Hydrochloric Acid SCHEMBL9004376 | 0.68 | HCN1 (0.49) | HCN1HCN4CYP1A2CYP2D6TSHR | |
| SCHEMBL9004398 | 0.64 | HCN1 (0.42) | HCN1HCN4CYP1A2CYP2D6TSHR | |
| SCHEMBL9207850 | 0.62 | HCN1 (0.46) | HCN1HCN4CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431856-A2 | Heterocyclic compounds | ZENECA LIMITED (GB) | 1991-06-12 | — | — | EP | claimed |