Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2126763 | 0.81 | CYP1B1 (0.52) | MAPTALDH1A1CYP1B1TMEM97SIGMAR1 | |
| SCHEMBL9797265 | 0.77 | KCNH2 (0.46) | KCNH2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL9797262 | 0.77 | KCNH2 (0.46) | KCNH2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL9797271 | 0.75 | ALDH1A1 (0.47) | KCNH2MAPTALDH1A1KMT2ASMN1; SMN2 | |
| 4-Nitrobenzoic Acid SCHEMBL31121220 | 0.75 | TDP1 (0.58) | KCNH2MAPTALDH1A1KMT2AMEN1 | |
| 4-Nitrobenzoic Acid SCHEMBL32671588 | 0.75 | TDP1 (0.58) | KCNH2MAPTALDH1A1KMT2AMEN1 | |
| 4-Nitrobenzoic Acid SCHEMBL31121240 | 0.75 | TDP1 (0.58) | KCNH2MAPTALDH1A1KMT2AMEN1 | |
| Dymanthine SCHEMBL31121223 | 0.75 | TDP1 (0.58) | KCNH2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL9796843 | 0.74 | KCNH2 (0.46) | KCNH2MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL9796857 | 0.74 | KCNH2 (0.46) | KCNH2MAPTALDH1A1TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406888-A2 | Nonlinear optical polymer composition and method for producing the same | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |